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Description DABCYL acid is one of the most popular acceptors for developing FRET-based nucleic acid probes suh as Molecular Beacon-based PCR probes. It is also used to prepare a variety of FRET peptides that are often used for the detection of various proteases. It is predominantly paired with EDANS (as fluorescence donor) in FRET-based fluorescent probes. [1] Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases Authors: Qing Xiao, Feiran Zhang, Benjamin A Nacev, Jun O Liu, Dehua Pei Journal: Biochemistry (2010): 5588--5599 |
